Clindamycin and vaginal bleeding

Background: We retrospectively examined the usefulness of antibiotic therapy for management of first-trimester threatened abortion in women with previous spontaneous abortion. Methods: From through , women with first-trimester threatened abortion received antibiotic therapy. Only those with gestational age less than 9 weeks and previous spontaneous abortion were included in this analysis. Women with mild abdominal cramping received amoxicillin plus erythromycin for 1 week; those with severe abdominal pain received amoxicillin plus clindamycin for 1 week. Recurrence was documented on the basis of either lower abdominal pain or vaginal bleeding.
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Can Clindamycin cause vaginal bleeding?

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Can Clindamycin cause vaginal bleeding?

Metrics details. The primary objective of this study was to investigate if supplementary lactobacilli treatment could improve the initial cure rate after vaginal clindamycin therapy, and secondly, if lactobacilli as repeated adjunct treatment during 3 menstrual cycles could lengthen the time to relapse after initial cure. However, any patient with missing or unclassified smears at the initial visit who continued the study and whose next smear indicated a cure was included in the cured group; the study also excluded two of the patients in the lactobacilli group who reported that they did not take any vaginal capsules. The 76 cured women were followed for 6 menstrual cycles or until relapse within that time span. At the end of the study, Adjuvant therapy with lactobacilli contributed significantly to avoidance of relapse with a proportional Hazard Risk ratio HR of 0. The study shows that supplementary treatment combining two different strains of probiotic lactobacilli does not improve the efficacy of BV therapy during the first month of treatment, but for women initially cured, adjunct treatment of lactobacilli during 3 menstrual cycles lengthens the time to relapse significantly in that more women remained BV free at the end of the 6-month follow up.
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7 Colors Your Vaginal Discharge Can Be (and What They Might Mean)

Bacterial vaginosis: What do I need to know about prescribing intravaginal clindamycin? Last revised in October Summary Have I got the right topic?
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Online ahead of Print ; 15 1 :e Introduction: Clindamycin is the preferred antimicrobial agent in the treatment of septic abortions. However, the administration of this medication may be associated with side effects. We describe the uncommon case of a patient who developed chest pain and sinus bradycardia following the administration of clindamycin. Case Presentation: A year-old primigravid woman presented herself to Shahid Motaharri Hospital Urmia, Iran with high grade fever and severe pain in the hypogastrium.
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